In episode 15 of season 6 of Inside the Science we’re highlighting the study, “Efficacy, safety, and dose-dependence of the analgesic effects of opioid therapy for people with osteoarthritis: systematic review and meta-analysis” with Dr. Christina Abdel Shaheed. She shares some of what prompted this study, the dilemma related to the use of opioids for patients with osteoarthritis, the results of the placebo-controlled studies which were included in this systematic review, the responsibility she feels clinicians have in informing the public of these results, the clinical implications and the big takeaways.